Human Cadherin like 23 (CDH23) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CDH23
Locus ID	64072
Kit Components	GA111955G1, Cadherin like 23 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111955G2, Cadherin like 23 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111955G3, Cadherin like 23 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001171930, NM_001171931, NM_001171932, NM_001171933, NM_001171934, NM_001171935, NM_001171936, NM_022124, NM_052836
Synonyms	CDHR23; USH1D
Summary	This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described. [provided by RefSeq, May 2013]

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