Human SH2D4A activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SH2D4A
Locus ID	63898
Kit Components	GA111904G1, SH2D4A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111904G2, SH2D4A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111904G3, SH2D4A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001174159, NM_001174160, NM_022071, NM_001363111, NR_156444, NM_001363110
Synonyms	PPP1R38; SH2A
Summary	Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.[UniProtKB/Swiss-Prot Function]

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