Human LGR7 (RXFP1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RXFP1
Locus ID	59350
Kit Components	GA111834G1, LGR7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111834G2, LGR7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111834G3, LGR7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001253727, NM_001253728, NM_001253729, NM_001253730, NM_001253732, NM_001253733, NM_021634, NR_045579, NR_045580, NR_045581, NR_045582, NR_045583, NR_045584, NM_001363776
Synonyms	LGR7; RXFPR1
Summary	This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane receptor superfamily. The encoded protein plays a critical role in sperm motility, pregnancy and parturition as a receptor for the protein hormone relaxin. Decreased expression of this gene may play a role in endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

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