Human ICEBERG (CARD18) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CARD18
Locus ID	59082
Kit Components	GA111810G1, ICEBERG gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111810G2, ICEBERG gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111810G3, ICEBERG gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_021571
Synonyms	ICEBERG; pseudo-ICE; UNQ5804
Summary	Inhibits generation of IL-1-beta by interacting with caspase-1 and preventing its association with RIP2. Down-regulates the release of IL1B.[UniProtKB/Swiss-Prot Function]

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