Human Neuroligin 4 (NLGN4X) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NLGN4X
Locus ID	57502
Kit Components	GA111541G1, Neuroligin 4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111541G2, Neuroligin 4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111541G3, Neuroligin 4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001282145, NM_001282146, NM_020742, NM_181332
Synonyms	ASPGX2; AUTSX2; HLNX; HNL4X; NLGN4
Summary	This gene encodes a member of the type-B carboxylesterase/lipase protein family. The encoded protein belongs to a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs large homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

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