Human FAM62B (ESYT2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ESYT2
Locus ID	57488
Kit Components	GA111530G1, FAM62B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111530G2, FAM62B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111530G3, FAM62B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_020728, NM_001367773
Synonyms	CHR2SYT; E-Syt2; FAM62B
Summary	Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding; this occurs most likely via the AP-2 complex.[UniProtKB/Swiss-Prot Function]

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