Human TRP 7 (TRPC7) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TRPC7
Locus ID	57113
Kit Components	GA111380G1, TRP 7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111380G2, TRP 7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111380G3, TRP 7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001167576, NM_001167577, NM_020389
Synonyms	TRP7
Summary	Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular calcium store depletion.[UniProtKB/Swiss-Prot Function]

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