Human PNO1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PNO1
Locus ID	56902
Kit Components	GA111255G1, PNO1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111255G2, PNO1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111255G3, PNO1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001329916, NM_001329917, NM_020143, NR_138146
Synonyms	KHRBP1; RRP20
Summary	Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA (PubMed:25851604).[UniProtKB/Swiss-Prot Function]

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