Human CTPS2 activation kit by CRISPRa

CAT#: GA111188

CTPS2 CRISPRa kit - CRISPR gene activation of human CTP synthase 2



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
CTPS2 Antibody - N-terminal region
    • 100 ul

CNY 5,250.00


CTPS2 (Myc-DDK-tagged)-Human CTP synthase II (CTPS2), transcript variant 1
    • 10 ug

CNY 4,360.00


CTPS2 Antibody - middle region
    • 100 ul

CNY 5,250.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol CTPS2
Locus ID 56474
Kit Components

GA111188G1, CTPS2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111188G2, CTPS2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111188G3, CTPS2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001144002, NM_019857, NM_175859
Synonyms DKFZp686C17207; FLJ43358; MGC32997
Summary The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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