Human Acetyl CoA synthetase (ACSS2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ACSS2
Locus ID	55902
Kit Components	GA111050G1, Acetyl CoA synthetase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111050G2, Acetyl CoA synthetase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111050G3, Acetyl CoA synthetase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001076552, NM_001242393, NM_018677, NM_139274, NR_028046
Synonyms	ACAS2; ACECS; ACS; ACSA; dJ1161H23.1
Summary	This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]

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