Human RIOK2 activation kit by CRISPRa

CAT#: GA110964

RIOK2 CRISPRa kit - CRISPR gene activation of human RIO kinase 2



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
RIOK2 mouse monoclonal antibody, clone OTI3E11 (formerly 3E11)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


RIOK2 (Myc-DDK-tagged)-Human RIO kinase 2 (RIOK2), transcript variant 1
    • 10 ug

CNY 4,112.00


RIOK2 mouse monoclonal antibody, clone OTI5D11 (formerly 5D11)
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol RIOK2
Locus ID 55781
Kit Components

GA110964G1, RIOK2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA110964G2, RIOK2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA110964G3, RIOK2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001159749, NM_018343
Synonyms RIO2
Summary Serine/threonine-protein kinase involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in export of the 40S pre-ribosome particles (pre-40S) from the nucleus to the cytoplasm. Its kinase activity is required for the release of NOB1, PNO1 and LTV1 from the late pre-40S and the processing of 18S-E pre-rRNA to the mature 18S rRNA (PubMed:19564402). Regulates the timing of the metaphase-anaphase transition during mitotic progression, and its phosphorylation, most likely by PLK1, regulates this function (PubMed:21880710).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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