Human OGDHL activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	OGDHL
Locus ID	55753
Kit Components	GA110939G1, OGDHL gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110939G2, OGDHL gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110939G3, OGDHL gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001143996, NM_001143997, NM_018245, NM_001347819, NM_001347820, NM_001347821, NM_001347822, NM_001347823, NM_001347824, NM_001347825, NM_001347826, NR_144682, NR_144683, NR_144684, NR_144685, NR_144686
Summary	The protein encoded by this gene is similar to oxoglutarate dehydrogenase (OGDH) of the OGDH complex, which degrades glucose and glutamate. This gene encodes several isoforms, including some that appear to localize to mitochondria. The encoded protein down-regulates the AKT signaling cascade and can suppress the growth of cervical cancer cells. [provided by RefSeq, Dec 2016]

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