Human COA1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	COA1
Locus ID	55744
Kit Components	GA110931G1, COA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110931G2, COA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110931G3, COA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001321197, NM_001321198, NM_001321199, NM_001321200, NM_001321201, NM_001321202, NM_001321203, NM_001321204, NM_001321205, NM_018224, NR_047701, NR_135580, NR_135581, NR_135582, NR_135583, NM_001350924, NM_001350925, NM_001350926, NM_001350927, NM_001350928, NR_146941, NR_146940, NR_146942, NR_146943, NR_146944, NR_146945
Synonyms	C7orf44; MITRAC15
Summary	Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for assembly of mitochondrial respiratory chain complex I and complex IV.[UniProtKB/Swiss-Prot Function]

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