Human Girdin (CCDC88A) activation kit by CRISPRa

CAT#: GA110898

CCDC88A CRISPRa kit - CRISPR gene activation of human coiled-coil domain containing 88A



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Rabbit Polyclonal Anti-CCDC88A Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


CCDC88A (Myc-DDK-tagged)-Human coiled-coil domain containing 88A (CCDC88A), transcript variant 1
    • 10 ug

CNY 18,856.00


GIV Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol CCDC88A
Locus ID 55704
Kit Components

GA110898G1, Girdin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA110898G2, Girdin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA110898G3, Girdin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001135597, NM_001254943, NM_018084, NM_001365480
Synonyms APE; GIRDIN; GIV; GRDN; HkRP1; KIAA1212; PEHO
Summary This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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