Human IL17B Receptor (IL17RB) activation kit by CRISPRa
CAT#: GA110783
IL17RB CRISPRa kit - CRISPR gene activation of human interleukin 17 receptor B
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | IL17RB |
Locus ID | 55540 |
Kit Components | GA110783G1, IL17B Receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa, Target Sequence: CGCTTTTATCCCGGCGCCGC GA110783G2, IL17B Receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa, Target Sequence: CGACCTGCCCCAGCCTGGGA GA110783G3, IL17B Receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa, Target Sequence: TCTGTTCGGGTGGCGGGAAT 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_018725, NM_172234 |
Synonyms | CRL4; EVI27; IL17BR; IL17RH1 |
Summary | The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq, Jul 2008] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN401646 | IL17RB - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |