Human SAPS3 (PPP6R3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PPP6R3
Locus ID	55291
Kit Components	GA110679G1, SAPS3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110679G2, SAPS3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110679G3, SAPS3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001164160, NM_001164161, NM_001164162, NM_001164163, NM_001164164, NM_018312, NM_001352347, NM_001352348, NM_001352349, NM_001352350, NM_001352351, NM_001352352, NM_001352353, NM_001352354, NM_001352355, NM_001352356, NM_001352357, NM_001352358, NM_001352359, NM_001352360, NM_001352361, NM_001352362, NM_001352363, NM_001352364, NM_001352365, NM_001352366, NM_001352367, NM_001352368, NM_001352369, NM_001352370, NM_001352371, NM_001352372, NM_001352373, NM_001352374, NM_001352375, NM_001352376, NM_001352377, NM_001352378, NM_001352379, NM_001352380, NR_147965, NR_147966, NR_147967, NR_147968, NR_147969, NR_147970, NR_147971
Synonyms	C11orf23; PP6R3; SAP190; SAPL; SAPLa; SAPS3
Summary	Protein phosphatase regulatory subunits, such as SAPS3, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS3 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]).[supplied by OMIM, Nov 2010]

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