Human MOBK1B (MOB1A) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MOB1A
Locus ID	55233
Kit Components	GA110629G1, MOBK1B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110629G2, MOBK1B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110629G3, MOBK1B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001317110, NM_001317111, NM_001317112, NM_018221
Synonyms	C2orf6; MATS1; MOB1; Mob4B; MOBK1B; MOBKL1B
Summary	The protein encoded by this gene is a component of the Hippo signaling pathway, which controls organ size and tumor growth by enhancing apoptosis. Loss of the encoded protein results in cell proliferation and cancer formation. The encoded protein is also involved in the control of microtubule stability during cytokinesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]

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