Human EXD2 activation kit by CRISPRa
CAT#: GA110616
EXD2 CRISPRa kit - CRISPR gene activation of human exonuclease 3'-5' domain containing 2
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | EXD2 |
Locus ID | 55218 |
Kit Components | GA110616G1, EXD2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110616G2, EXD2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110616G3, EXD2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001193360, NM_001193361, NM_001193362, NM_001193363, NM_018199, NR_034164, NR_034165 |
Synonyms | C14orf114; EXDL2 |
Summary | Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN400127 | EXD2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |