Human Baf180 (PBRM1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PBRM1
Locus ID	55193
Kit Components	GA110592G1, Baf180 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110592G2, Baf180 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110592G3, Baf180 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_018165, NM_018313, NM_181041, NM_181042, NM_001350074, NM_001350075, NM_001350076, NM_001350077, NM_001350078, NM_001350079, NM_001366070, NM_001366071, NM_001366073, NM_001366074, NM_001366075, NM_001366072, NM_001366076
Synonyms	BAF180; MGC156155; MGC156156; PB1
Summary	This locus encodes a subunit of ATP-dependent chromatin-remodeling complexes. The encoded protein has been identified as in integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormone receptors. Mutations at this locus have been associated with primary clear cell renal cell carcinoma. [provided by RefSeq, Feb 2012]

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