Human ARHGEF10L activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ARHGEF10L
Locus ID	55160
Kit Components	GA110563G1, ARHGEF10L gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110563G2, ARHGEF10L gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110563G3, ARHGEF10L gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001011722, NM_001319837, NM_001319838, NM_001328124, NM_018125, NR_137287, NR_137288
Synonyms	GrinchGEF
Summary	This gene belongs to the RhoGEF subfamily of RhoGTPases. Members of this subfamily are activated by specific guanine nucleotide exchange factors (GEFs) and are involved in signal transduction. The encoded protein shows cytosolic distribution. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2016]

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