Human ATG16L1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ATG16L1
Locus ID	55054
Kit Components	GA110481G1, ATG16L1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110481G2, ATG16L1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110481G3, ATG16L1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001190266, NM_001190267, NM_017974, NM_030803, NM_198890, NM_001363742
Synonyms	APG16L; ATG16A; ATG16L; IBD10; WDR30
Summary	The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2010]

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