Human COMMD4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	COMMD4
Locus ID	54939
Kit Components	GA110388G1, COMMD4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110388G2, COMMD4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110388G3, COMMD4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001284377, NM_001284378, NM_001284379, NM_001321844, NM_001321845, NM_001321846, NM_001321847, NM_001321848, NM_017828, NR_104312, NR_104313
Summary	May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). Down-regulates activation of NF-kappa-B.[UniProtKB/Swiss-Prot Function]

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