Human LAX1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LAX1
Locus ID	54900
Kit Components	GA110355G1, LAX1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110355G2, LAX1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110355G3, LAX1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001136190, NM_001282878, NM_017773
Synonyms	LAX
Summary	Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells.[UniProtKB/Swiss-Prot Function]

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