Human WDR74 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	WDR74
Locus ID	54663
Kit Components	GA110212G1, WDR74 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110212G2, WDR74 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110212G3, WDR74 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001307977, NM_018093, NM_001369447, NM_001369453, NR_161381, NM_001369448, NM_001369449, NM_001369450, NM_001369451
Summary	Regulatory protein of the MTREX-exosome complex involved in the synthesis of the 60S ribosomal subunit (PubMed:26456651). Participates in an early cleavage of the pre-rRNA processing pathway in cooperation with NVL (PubMed:29107693). Required for blastocyst formation, is necessary for RNA transcription, processing and/or stability during preimplantation development (By similarity).[UniProtKB/Swiss-Prot Function]

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