Human IL20 Receptor alpha (IL20RA) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	IL20RA
Locus ID	53832
Kit Components	GA110029G1, IL20 Receptor alpha gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110029G2, IL20 Receptor alpha gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110029G3, IL20 Receptor alpha gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001278722, NM_001278723, NM_001278724, NM_014432
Synonyms	CRF2-8; IL-20R-alpha; IL-20R1; IL-20RA
Summary	This gene encodes a member of the type II cytokine receptor family. The encoded protein is a subunit of the receptor for interleukin 20, a cytokine that may be involved in epidermal function. The interleukin 20 receptor is a heterodimeric complex consisting of the encoded protein and interleukin 20 receptor beta. This gene and interleukin 20 receptor beta are highly expressed in skin, and are upregulated in psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

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