Human KCNK4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KCNK4
Locus ID	50801
Kit Components	GA109446G1, KCNK4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109446G2, KCNK4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109446G3, KCNK4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001317090, NM_016611, NM_033310, NM_033311, NR_133660, NR_133661
Synonyms	K2p4.1; K2P4.1 potassium channel; potassium channel, subfamily K, member 4; TRAAK; TRAAK, DKFZP566E164; TRAAK1; TWIK-related arachidonic acid-stimulated potassium channel protein; two pore K+ channel KT4.1
Summary	This gene encodes a member of the TWIK-related arachidonic acid-stimulated two pore potassium channel subfamily. The encoded protein homodimerizes and functions as an outwardly rectifying channel. This channel is regulated by polyunsaturated fatty acids, temperature and mechanical deformation of the lipid membrane. This protein is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia neurons. Alternate splicing results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream testis expressed 40 (TEX40) gene, as represented in GeneID: 106780802. [provided by RefSeq, Nov 2015]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.