Human VSX1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	VSX1
Locus ID	30813
Kit Components	GA109383G1, VSX1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109383G2, VSX1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109383G3, VSX1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001256271, NM_001256272, NM_014588, NM_199425, NR_045948, NR_045951
Synonyms	CAASDS; KTCN; KTCN1; PPCD; PPCD1; PPD; RINX
Summary	The protein encoded by this gene contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy and keratoconus. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

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