Human SH3KBP1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SH3KBP1
Locus ID	30011
Kit Components	GA109376G1, SH3KBP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109376G2, SH3KBP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109376G3, SH3KBP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001024666, NM_001184960, NM_031892, NM_001353890, NM_001353891, NM_001353892, NM_001353893, NM_001353894, NM_001353895, NM_001353897
Synonyms	CD2BP3; CIN85; GIG10; HSB-1; HSB1; MIG18
Summary	This gene encodes an adapter protein that contains one or more N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017]

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