Human MADM (NRBP1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NRBP1
Locus ID	29959
Kit Components	GA109343G1, MADM gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109343G2, MADM gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109343G3, MADM gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_013392, NM_001321357, NM_001321358, NM_001321359, NM_001321361, NM_001321362, NM_001321363
Synonyms	BCON3; MADM; MUDPNP; NRBP
Summary	May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication.[UniProtKB/Swiss-Prot Function]

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