Human AP4 (REPIN1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	REPIN1
Locus ID	29803
Kit Components	GA109277G1, AP4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109277G2, AP4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109277G3, AP4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001099695, NM_001099696, NM_013400, NM_014374, NM_001362746, NM_001362745, NM_001362747
Synonyms	AP4; RIP60; Zfp464; ZNF464
Summary	Sequence-specific double-stranded DNA-binding protein required for initiation of chromosomal DNA replication. Binds on 5'-ATT-3' reiterated sequences downstream of the origin of bidirectional replication (OBR) and a second, homologous ATT sequence of opposite orientation situated within the OBR zone. Facilitates DNA bending.[UniProtKB/Swiss-Prot Function]

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