Human PHPT1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PHPT1
Locus ID	29085
Kit Components	GA109220G1, PHPT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109220G2, PHPT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109220G3, PHPT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001135860, NM_001135861, NM_001287342, NM_001287343, NM_014172, NR_109807, NR_109808
Synonyms	CGI-202; HEL-S-132P; HSPC141; PHP14
Summary	This gene encodes an enzyme that catalyzes the reversible dephosphorylation of histidine residues in proteins. It may be involved in the dephosphorylation of G-beta and ATP citrate lyase and in negatively regulating CD4 T lymphocytes by dephosphorylation and inhibition of KCa3.1 channels. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

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