Human DISC1 activation kit by CRISPRa

CAT#: GA109058

DISC1 CRISPRa kit - CRISPR gene activation of human DISC1 scaffold protein



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Anti-DISC1 Rabbit Polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


DISC1 (Myc-DDK-tagged)-Human disrupted in schizophrenia 1 (DISC1), transcript variant L
    • 10 ug

CNY 6,256.00
CNY 8,930.00


Rabbit Polyclonal anti-DISC1 Antibody
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol DISC1
Locus ID 27185
Kit Components

GA109058G1, DISC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109058G2, DISC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109058G3, DISC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001012957, NM_001012958, NM_001012959, NM_001164537, NM_001164538, NM_001164539, NM_001164540, NM_001164541, NM_001164542, NM_001164544, NM_001164545, NM_001164546, NM_001164547, NM_001164548, NM_001164549, NM_001164550, NM_001164551, NM_001164552, NM_001164553, NM_001164554, NM_001164555, NM_001164556, NM_018662
Synonyms C1orf136; SCZD9
Summary This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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