Human ELYS (AHCTF1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	AHCTF1
Locus ID	25909
Kit Components	GA108623G1, ELYS gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108623G2, ELYS gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108623G3, ELYS gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001323342, NM_001323343, NM_015446, NM_175865, NR_136586
Synonyms	ELYS; MST108; MSTP108; TMBS62
Summary	Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the Nup107-160 subcomplex of the NPC. Also required for the localization of the Nup107-160 subcomplex of the NPC to the kinetochore during mitosis and for the completion of cytokinesis.[UniProtKB/Swiss-Prot Function]

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