Human MTHFD1L activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MTHFD1L
Locus ID	25902
Kit Components	GA108618G1, MTHFD1L gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108618G2, MTHFD1L gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108618G3, MTHFD1L gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001242767, NM_001242768, NM_001242769, NM_015440, NM_001350486, NM_001350487, NM_001350488, NM_001350489, NM_001350490, NM_001350491, NM_001350492, NM_001350493, NR_146719, NR_146720
Synonyms	dJ292B18.2; FTHFSDC1; MTC1THFS
Summary	The protein encoded by this gene is involved in the synthesis of tetrahydrofolate (THF) in the mitochondrion. THF is important in the de novo synthesis of purines and thymidylate and in the regeneration of methionine from homocysteine. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2011]

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