Human PLEKHG4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PLEKHG4
Locus ID	25894
Kit Components	GA108611G1, PLEKHG4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108611G2, PLEKHG4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108611G3, PLEKHG4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001129727, NM_001129728, NM_001129729, NM_001129731, NM_015432
Synonyms	ARHGEF44; PRTPHN1; SCA4
Summary	The protein encoded by this gene can function as a guanine nucleotide exchange factor (GEF) and may play a role in intracellular signaling and cytoskeleton dynamics at the Golgi apparatus. Polymorphisms in the region of this gene have been found to be associated with spinocerebellar ataxia in some study populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

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