Human RASGRP3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RASGRP3
Locus ID	25780
Kit Components	GA108532G1, RASGRP3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108532G2, RASGRP3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108532G3, RASGRP3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001139488, NM_015376, NM_170672, NM_001349975, NM_001349976, NM_001349977, NM_001349978, NM_001349979, NM_001349980, NM_001349981
Synonyms	GRP3
Summary	The protein encoded by this gene is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in this gene have been associated with systemic lupus erythematosus and several cancers. [provided by RefSeq, Mar 2017]

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