Human GABARAPL1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GABARAPL1
Locus ID	23710
Kit Components	GA108480G1, GABARAPL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108480G2, GABARAPL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108480G3, GABARAPL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_031412, NM_001363598
Synonyms	APG8-LIKE; APG8L; ATG8; ATG8B; ATG8L; GEC1
Summary	Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.[UniProtKB/Swiss-Prot Function]

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