Human GPR161 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GPR161
Locus ID	23432
Kit Components	GA108306G1, GPR161 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108306G2, GPR161 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108306G3, GPR161 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001267609, NM_001267610, NM_001267611, NM_001267612, NM_001267613, NM_001267614, NM_007369, NM_153832, NM_001349632, NM_001349633, NM_001349634, NM_001349635
Synonyms	RE2
Summary	The protein encoded by this gene is an orphan G protein-coupled receptor whose ligand is unknown. This gene is overexpressed in triple-negative breast cancer, and disruption of this gene slows the proliferation of basal breast cancer cells. Therefore, this gene is a potential drug target for triple-negative breast cancer. [provided by RefSeq, Mar 2017]

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