Human SIRT3 activation kit by CRISPRa

CAT#: GA108288

SIRT3 CRISPRa kit - CRISPR gene activation of human sirtuin 3



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
SIRT3 Rabbit polyclonal Antibody
    • 100 ul

CNY 2,700.00

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SIRT3 (Myc-DDK-tagged)-Human sirtuin 3 (SIRT3), nuclear gene encoding mitochondrial protein, transcript variant 1
    • 10 ug

CNY 5,488.00


SIRT3 Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol SIRT3
Locus ID 23410
Kit Components

GA108288G1, SIRT3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108288G2, SIRT3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108288G3, SIRT3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001017524, NM_012239, NM_001370312, NM_001370314, NM_001370316, NM_001370318, NM_001370319, NM_001370325, NR_163386, NR_163388, NR_163389, NR_163390, NR_163391, NR_163393, NR_163394, NR_163398, NR_163399, NR_163400, NR_163401, NM_001370310, NM_001370315, NM_001370317, NM_001370320, NM_001370321, NM_001370322, NM_001370323, NM_001370324, NR_163387, NR_163392, NR_163395, NR_163396, NR_163397, NR_163402
Synonyms SIR2L3
Summary SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and prevent the formation of cancer cells. SIRT3 has far-reaching effects on nuclear gene expression, cancer, cardiovascular disease, neuroprotection, aging, and metabolic control. [provided by RefSeq, May 2019]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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