Human MPRIP activation kit by CRISPRa
CAT#: GA108086
MPRIP CRISPRa kit - CRISPR gene activation of human myosin phosphatase Rho interacting protein
CNY 12,255.00
CNY 19,855.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | MPRIP |
Locus ID | 23164 |
Kit Components | GA108086G1, MPRIP gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108086G2, MPRIP gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108086G3, MPRIP gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_015134, NM_201274, NM_001364716 |
Synonyms | M-RIP; MRIP; p116Rip; RHOIP3; RIP3 |
Summary | Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
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KN211386 | MPRIP - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
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KN211386BN | MPRIP - human gene knockout kit via CRISPR, HDR mediated |
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KN211386LP | MPRIP - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
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KN211386RB | MPRIP - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
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KN411386 | MPRIP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |