Human ZC3H3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ZC3H3
Locus ID	23144
Kit Components	GA108072G1, ZC3H3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108072G2, ZC3H3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108072G3, ZC3H3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_015117
Synonyms	ZC3HDC3
Summary	Required for the export of polyadenylated mRNAs from the nucleus (PubMed:19364924). Enhances ACVR1B-induced SMAD-dependent transcription. Binds to single-stranded DNA but not to double-stranded DNA in vitro. Involved in RNA cleavage (By similarity).[UniProtKB/Swiss-Prot Function]

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