Human Neurofascin (NFASC) activation kit by CRISPRa
CAT#: GA108048
NFASC CRISPRa kit - CRISPR gene activation of human neurofascin
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | NFASC |
Locus ID | 23114 |
Kit Components | GA108048G1, Neurofascin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108048G2, Neurofascin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108048G3, Neurofascin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001005387, NM_001005388, NM_001005389, NM_001160331, NM_001160332, NM_001160333, NM_015090, NM_001365986 |
Synonyms | DKFZp686P2250; FLJ46866; KIAA0756; NF; NRCAML |
Summary | This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.[provided by RefSeq, May 2009] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN414686 | NFASC - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |