Human Neurofascin (NFASC) activation kit by CRISPRa

CAT#: GA108048

NFASC CRISPRa kit - CRISPR gene activation of human neurofascin



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Goat Anti-Neurofascin / NFASC (aa877-890) Antibody
    • 100 ug

CNY 5,371.00


NFASC (Myc-DDK-tagged)-Human neurofascin (NFASC), transcript variant 2
    • 10 ug

CNY 8,280.00


Nfasc186 mouse monoclonal antibody,clone OTI11A7
    • 30 ul

CNY 870.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol NFASC
Locus ID 23114
Kit Components

GA108048G1, Neurofascin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108048G2, Neurofascin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108048G3, Neurofascin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001005387, NM_001005388, NM_001005389, NM_001160331, NM_001160332, NM_001160333, NM_015090, NM_001365986
Synonyms DKFZp686P2250; FLJ46866; KIAA0756; NF; NRCAML
Summary This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.[provided by RefSeq, May 2009]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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