Human ANKRD6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ANKRD6
Locus ID	22881
Kit Components	GA107879G1, ANKRD6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107879G2, ANKRD6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107879G3, ANKRD6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001242809, NM_001242811, NM_001242813, NM_001242814, NM_014942
Synonyms	FLJ12637; FLJ34916
Summary	Recruits CKI-epsilon to the beta-catenin degradation complex that consists of AXN1 or AXN2 and GSK3-beta and allows efficient phosphorylation of beta-catenin, thereby inhibiting beta-catenin/Tcf signals.[UniProtKB/Swiss-Prot Function]

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