Human FILIP1L activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FILIP1L
Locus ID	11259
Kit Components	GA107758G1, FILIP1L gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107758G2, FILIP1L gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107758G3, FILIP1L gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001042459, NM_001282793, NM_001282794, NM_014890, NM_182909, NM_001370247
Synonyms	DOC-1; DOC1; GIP90; GIP130
Summary	Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor-associated vasculature.[UniProtKB/Swiss-Prot Function]

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