Human KAT7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KAT7
Locus ID	11143
Kit Components	GA107666G1, KAT7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107666G2, KAT7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107666G3, KAT7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001199155, NM_001199156, NM_001199157, NM_001199158, NM_007067, NM_001346706
Synonyms	HBO1; HBOA; MYST2; ZC2HC7
Summary	The protein encoded by this gene is part of the multimeric HBO1 complex, which possesses histone H4-specific acetyltransferase activity. This activity is required for functional replication origins and is involved in transcriptional activation of some genes. In both cases, the acetylation of histone H4 helps unfold chromatin so that the DNA can be accessed and replicated or transcribed. [provided by RefSeq, Oct 2016]

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