Human Cyclin (CCNI) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CCNI
Locus ID	10983
Kit Components	GA107541G1, Cyclin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107541G2, Cyclin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107541G3, Cyclin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_006835, NM_001348132, NM_001348133, NM_001348134, NM_001348135, NM_001348136, NM_001348137, NM_001348138, NM_001348139, NM_001348140
Synonyms	CCNI1; CYC1; CYI
Summary	The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin shows the highest similarity with cyclin G. The transcript of this gene was found to be expressed constantly during cell cycle progression. [provided by RefSeq, Jan 2017]

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