Human DMRT2 activation kit by CRISPRa
CAT#: GA107303
DMRT2 CRISPRa kit - CRISPR gene activation of human doublesex and mab-3 related transcription factor 2
CNY 12,255.00
CNY 8,930.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | DMRT2 |
Locus ID | 10655 |
Kit Components | GA107303G1, DMRT2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107303G2, DMRT2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107303G3, DMRT2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001130865, NM_006557, NM_181872, NM_001370531, NM_001370532, NM_001370533, NR_163472 |
Synonyms | doublesex and mab-3 related transcription factor 2; OTTHUMP00000020964; OTTHUMP00000020965; OTTHUMP00000020966; OTTHUMP00000020967; terra-like protein |
Summary | The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. [provided by RefSeq, Apr 2010] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN421391 | DMRT2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |