Human AHA1 (AHSA1) activation kit by CRISPRa
CAT#: GA107253
AHSA1 CRISPRa kit - CRISPR gene activation of human activator of HSP90 ATPase activity 1
CNY 12,255.00
CNY 1,999.00
CNY 2,700.00
CNY 3,656.00
CNY 3,990.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | AHSA1 |
Locus ID | 10598 |
Kit Components | GA107253G1, AHA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107253G2, AHA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107253G3, AHA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_012111, NM_001321441 |
Synonyms | AHA1; C14orf3; p38 |
Summary | Acts as a co-chaperone of HSP90AA1 (PubMed:29127155). Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity (PubMed:29127155). Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:27353360). Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:29127155).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN401782 | AHSA1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |