Human DRP1 (DNM1L) activation kit by CRISPRa

CAT#: GA106816

DNM1L CRISPRa kit - CRISPR gene activation of human dynamin 1 like



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
DNM1L mouse monoclonal antibody, clone OTI4F6 (formerly 4F6)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


DNM1L (Myc-DDK-tagged)-Human dynamin 1-like (DNM1L), transcript variant 2
    • 10 ug

CNY 5,200.00


DNM1L mouse monoclonal antibody, clone OTI4A4 (formerly 4A4)
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol DNM1L
Locus ID 10059
Kit Components

GA106816G1, DRP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106816G2, DRP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106816G3, DRP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001278463, NM_001278464, NM_001278465, NM_001278466, NM_001330380, NM_005690, NM_012062, NM_012063
Synonyms DLP1; DRP1; DVLP; DYMPLE; EMPF; EMPF1; HDYNIV
Summary This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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