Human ARNT2 activation kit by CRISPRa

CAT#: GA106701

ARNT2 CRISPRa kit - CRISPR gene activation of human aryl hydrocarbon receptor nuclear translocator 2



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Rabbit polyclonal ARNT2 Antibody (Center)
    • 400 ul

CNY 6,160.00


ARNT2 (Myc-DDK-tagged)-Human aryl-hydrocarbon receptor nuclear translocator 2 (ARNT2)
    • 10 ug

CNY 5,256.00
CNY 5,800.00


ARNT2 Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol ARNT2
Locus ID 9915
Kit Components

GA106701G1, ARNT2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106701G2, ARNT2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106701G3, ARNT2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_014862
Synonyms bHLHe1; WEDAS
Summary This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. [provided by RefSeq, Dec 2013]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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